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Frank J P M Huygen Selected Research

Complex Regional Pain Syndromes

11/2021Effect of intravenous low-dose S-ketamine on pain in patients with Complex Regional Pain Syndrome: A retrospective cohort study.
10/2019Highlighting the Role of Biomarkers of Inflammation in the Diagnosis and Management of Complex Regional Pain Syndrome.
1/2018Spinal Cord Stimulation in Patients With Complex Regional Pain Syndrome: A Possible Target for Immunomodulation?
1/2018Dorsal Column Stimulation vs. Dorsal Root Ganglion Stimulation for Complex Regional Pain Syndrome Confined to the Knee: Patients' Preference Following the Trial Period.
1/2016Pathophysiological Mechanisms Involved in Vasomotor Disturbances in Complex Regional Pain Syndrome and Implications for Therapy: A Review.
7/2015Burst Spinal Cord Stimulation in a Patient with Complex Regional Pain Syndrome: A 2-year Follow-Up.
11/2013Report of a preliminary discontinued double-blind, randomized, placebo-controlled trial of the anti-TNF-α chimeric monoclonal antibody infliximab in complex regional pain syndrome.
9/2009Regulation of peripheral blood flow in complex regional pain syndrome: clinical implication for symptomatic relief and pain management.
9/2009No recovery of cold complex regional pain syndrome after transdermal isosorbide dinitrate: a small controlled trial.
10/2008Effect of tadalafil on blood flow, pain, and function in chronic cold complex regional pain syndrome: a randomized controlled trial.
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Frank J P M Huygen Research Topics

Disease

26Pain (Aches)
01/2022 - 02/2004
15Complex Regional Pain Syndromes
11/2021 - 12/2005
8Chronic Pain
05/2022 - 05/2010
7Blister (Bulla)
01/2018 - 02/2002
4Inflammation (Inflammations)
10/2019 - 05/2012
4Neuralgia (Stump Neuralgia)
06/2018 - 07/2008
3Low Back Pain (Lumbago)
01/2020 - 01/2013
3Necrosis
12/2005 - 02/2002
2Intractable Pain
01/2022 - 11/2021
2Dystonia (Limb Dystonia)
10/2020 - 08/2012
1Back Pain (Backache)
01/2022
1Nausea
12/2021
1Myocardial Ischemia (Ischemic Heart Diseases)
01/2021
1Seizures (Absence Seizure)
01/2021
1Flushing
01/2021
1Hyperthermia
01/2021
1Cardiac Arrhythmias (Arrythmia)
01/2021
1Headache (Headaches)
01/2021
1Spinal Cord Injuries (Spinal Cord Injury)
01/2021
1Cellulitis
01/2021
1Stroke (Strokes)
01/2021
1Autonomic Dysreflexia
01/2021
1Hemorrhage
01/2021
1Abscess
01/2021
1Intervertebral Disc Displacement (Herniated Disc)
01/2020
1Nerve Compression Syndromes (Nerve Entrapment)
01/2018
1Abdominal Pain (Pain, Abdominal)
01/2018
1Agranulocytosis (Granulocytopenia)
12/2017
1Lacerations
10/2017
1Respiratory Insufficiency (Respiratory Failure)
01/2017
1Opioid-Induced Constipation
01/2016
1Atopic Dermatitis (Atopic Eczema)
01/2016
1Musculoskeletal Pain
01/2016
1Reflex Sympathetic Dystrophy (Reflex Sympathetic Dystrophy Syndrome)
01/2015
1Autoimmune Diseases (Autoimmune Disease)
01/2015
1Cluster Headache (Cluster Headaches)
11/2013
1Paresthesia (Dysesthesia)
09/2013
1Failed Back Surgery Syndrome
01/2013

Drug/Important Bio-Agent (IBA)

7CytokinesIBA
01/2018 - 02/2002
5Interleukin-6 (Interleukin 6)IBA
01/2008 - 02/2002
5Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2008 - 02/2002
4Opioid Analgesics (Opioids)IBA
01/2022 - 01/2016
3SteroidsIBA
01/2020 - 12/2017
3Analgesics (Analgesic Drugs)IBA
12/2017 - 04/2003
3Endothelin-1 (Endothelin 1)IBA
09/2009 - 11/2006
2KetamineFDA LinkGeneric
01/2022 - 05/2010
2BaclofenFDA LinkGeneric
01/2021 - 01/2021
2Pharmaceutical PreparationsIBA
10/2020 - 10/2017
2Remifentanil (Ultiva)FDA Link
10/2019 - 01/2017
2DexmedetomidineFDA Link
01/2017 - 01/2017
2Inflammation MediatorsIBA
05/2012 - 12/2005
2Isosorbide Dinitrate (Isordil)FDA LinkGeneric
09/2009 - 01/2008
2InterleukinsIBA
12/2005 - 02/2002
1Anti-Bacterial Agents (Antibiotics)IBA
01/2022
1EsketamineIBA
11/2021
1Retinaldehyde (Retinal)IBA
01/2021
1Propofol (Diprivan)FDA LinkGeneric
10/2019
1Biomarkers (Surrogate Marker)IBA
10/2019
1SolutionsIBA
06/2018
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2018
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2018
1ChemokinesIBA
01/2018
1Lidocaine (Xylocaine)FDA LinkGeneric
01/2018
1MethylprednisoloneFDA LinkGeneric
01/2018
1AntipyreticsIBA
12/2017
1Dipyrone (Metamizole)IBA
12/2017
1Parasympatholytics (Antispasmodics)IBA
12/2017
1Nerve Growth Factors (Neurotrophins)IBA
01/2017
1Hypnotics and Sedatives (Sedatives)IBA
01/2017
1salicylhydroxamic acid (SHAM)IBA
11/2016
1Estradiol (Delestrogen)FDA LinkGeneric
01/2016
1Gonadal Steroid Hormones (Sex Hormones)IBA
01/2016
1LaxativesIBA
01/2016
1Oxycodone (Oxycontin)FDA LinkGeneric
01/2016
1Androstenedione (4 Androstene 3,17 dione)IBA
01/2016
1Hormones (Hormone)IBA
01/2016
117-alpha-Hydroxyprogesterone (17 Hydroxyprogesterone)IBA
01/2016
1AutoantibodiesIBA
01/2015
1Antinuclear AntibodiesIBA
01/2015
1FlavoproteinsIBA
01/2014
1Monoclonal AntibodiesIBA
11/2013
1Infliximab (Remicade)FDA Link
11/2013
1HLA-DQ8 antigenIBA
08/2012
1HLA-DQB1 antigen (HLA DQB1)IBA
08/2012

Therapy/Procedure

16Therapeutics
05/2022 - 09/2009
6Spinal Cord Stimulation
05/2022 - 09/2013
2Pain Management
12/2021 - 09/2009
2Catheters
01/2021 - 10/2017
2Denervation
01/2020 - 07/2017
2Injections
01/2020 - 01/2018
2Anesthesia
01/2017 - 11/2009
1Laparoscopic Cholecystectomy
12/2021
1Operative Surgical Procedures
12/2021
1Emergency Treatment
01/2021
1Analgesia
10/2019
1Artificial Skin
01/2018
1Immunomodulation
01/2018
1Hormone Replacement Therapy (Therapy, Hormone Replacement)
01/2016
1Aftercare (After-Treatment)
07/2015
1Conservative Treatment
01/2013